Recent Rethinking Clinical Trials Grand Rounds sessions covered the COMPARE-Pediatric IBD study, a hypertension self-management texting intervention for Black Veterans, and the upcoming Pediatric Trials Network presentation.
Biogen marked 30 years of U.S. manufacturing with a $2 billion RTP investment, while regional leaders urged deeper venture capital and research density to boost North Carolina's biotech competitiveness.
A world-first clinical trial testing immunotherapy for glioblastoma has opened in the US. The GIANT trial will evaluate Nivolumab and Relatlimab before surgery, with results expected in about two years. Three patients have been enrolled so far.
HHS Secretary Robert F. Kennedy Jr. announces major reorganization centralizing department operations under CMS leadership, while Duke University telehealth program shows 66% reduction in repeat ER visits for older adults who fall.
Ultrasound-activated bubbles show promise for cancer therapy. Duke's SonoPIN killed 50% of cancer cells, while Case Western nanobubbles broke down tumor barriers, enabling potential trials in two years.
Researchers at Duke University discovered that specialized immune cells called resident macrophages maintain the eye's drainage system and regulate pressure, potentially providing a new therapeutic target for glaucoma treatment beyond current symptom management approaches.
A study of 434 toddlers found no association between maternal mRNA COVID-19 vaccination during or shortly before pregnancy and autism or other neurodevelopmental disorders in offspring aged 18-30 months.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07764718 |
Temporal Interference Brain Stimulation for Adults With Drug-Resistant Epilepsy Undergoing Stereo-EEG Monitoring |
NOT_YET_RECRUITING | NA |
| NCT07738874 |
Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care |
NOT_YET_RECRUITING | NA |
| NCT07734701 |
Pregnenolone Treatment for Alcohol Use Disorder and Major Depressive Disorder |
NOT_YET_RECRUITING | PHASE2 |
| NCT07732829 |
FlexED: Full Threshold ED Substudy |
NOT_YET_RECRUITING | NA |
| NCT07725172 |
Radiation Therapy and Thymus Function in Young Women With Breast Cancer |
NOT_YET_RECRUITING | |
| NCT07714590 |
Effect of Periumbilical Vibration on Pain Perception During Intrauterine Device Insertion: A Randomized Controlled Trial |
NOT_YET_RECRUITING | NA |
| NCT07711366 |
INTEGRATE-RX: Integrating Clinical Pharmacists in HIV Care to Mitigate Last-Mile Challenges and Reduce Cardiovascular Disease Burden |
NOT_YET_RECRUITING | NA |
| NCT07702539 |
NASA Exercise Prebreathe Study |
NOT_YET_RECRUITING | NA |
| NCT07699614 |
Lung Health and the Microbiome Among Adults in Botswana: the Go-hema Cohort |
RECRUITING | |
| NCT07686692 |
IV Iron Therapy for Older Adults With Heart Failure With Preserved Ejection Fraction and Iron Deficiency |
NOT_YET_RECRUITING | PHASE4 |
