Silo Pharma received a European patent grant and a Japan patent allowance for SPC-15, its intranasal PTSD prevention candidate. The patents cover methods using serotonin 4 receptor agonists to prevent stress-induced psychiatric disorders.
Ivermectin is being promoted again for unproven uses like cancer and hantavirus, while several states consider making it available over the counter. Experts stress there is no clinical evidence for these uses and warn of serious side effects. Prescriptions among cancer patients have more than doubled.
Studies reveal context-dependent genetic effects in psychiatric disorders, reassuring evidence on prenatal antidepressant use, and findings on parental depression timing, diagnostic interview reliability, and rising self-diagnosis.
A $9 million grant from ASAP and The Michael J. Fox Foundation funds an Indiana University-led study on immune cell exhaustion in Parkinson's disease, aiming to develop personalized immunotherapies. The multi-institutional team will map immune system changes to uncover biomarkers and explain disease heterogeneity. Advances in proteomics are also enabling molecular subtyping and precision medicine across neurological disorders.
A longitudinal study of 460,000 teenagers found that adolescent cannabis use increases the risk of developing bipolar and psychotic disorders by twofold, as well as raising risks for depression and anxiety.
Acurx Pharmaceuticals announced a new clinical trial program for ibezapolstat in patients with recurrent C. difficile infection, building on Phase 2 results showing 96% clinical cure rates with no recurrence while sparing the gut microbiome.
Isomorphic Labs released a 27-page technical report on IsoDDE, its new AI drug-discovery engine that outperforms existing models in predicting drug-protein interactions and antibody structures, but the proprietary system offers limited technical details.
A population-based study of over 1.27 million births found SSRI antidepressants during pregnancy increase gestational diabetes risk but reduce preterm birth and low birth weight risks, with effects independent of maternal depression.
U.S. Health Secretary Robert F. Kennedy Jr. claimed ketogenic diets can cure schizophrenia, but psychiatry experts say the assertion goes far beyond what current scientific evidence supports.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07779226 |
DecNef for AVH in Schizophrenia |
NOT_YET_RECRUITING | PHASE1/PHASE2 |
| NCT07778823 |
Augmented Reality-Cardiopulmonary Resuscitation Support for Pediatric Resuscitation |
RECRUITING | NA |
| NCT07778524 |
Alpelisib Challenge Test (ACT) |
NOT_YET_RECRUITING | PHASE1 |
| NCT07772154 |
Virtual Tai Chi for Chronic Low Back Pain (Spine 2027) |
NOT_YET_RECRUITING | NA |
| NCT07756710 |
Ursodeoxycholic Acid in Barrett's Endotherapy |
NOT_YET_RECRUITING | |
| NCT07746427 |
Digital Mindfulness Meditation in Adolescents With Atopic Dermatitis |
RECRUITING | NA |
| NCT07745101 |
Research On Advanced Diagnostics and Management of All Pregnancies to Prevent Stillbirth (ROADMAPS) |
NOT_YET_RECRUITING | |
| NCT07744217 |
Identifying Biomarkers of Gastro Intestinal Comorbidities in Autism Spectrum Disorder |
COMPLETED | |
| NCT07743268 |
Personalized Antisense Oligonucleotide Therapy for Participants With TARDBP ALS |
ENROLLING_BY_INVITATION | PHASE1/PHASE2 |
| NCT07737275 |
Screening With Portable X-rays for Rapid Recognition of TB |
NOT_YET_RECRUITING | NA |
