Network Meta-analysis of Intermittent Fasting and Cardiometabolic Risk
NCT05309057 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 25
Last updated 2022-04-04
Summary
Intermittent fasting is a method of restricting calories over a defined period of time and includes regimens such as whole-day fasting, alternate-day fasting, and time-restricted feeding. There is emerging evidence that intermittent fasting or energy restriction might be more beneficial than continuous energy restriction for some risk factors. The effect of intermittent fasting on risk factors associated with obesity, diabetes, and cardiovascular disease, however, is not clear. The European Association for the Study of Diabetes (EASD) has yet to make any recommendations regarding the role of intermittent fasting in the management of diabetes. To inform the update of the EASD Clinical Practice Guidelines for Nutrition Therapy, tthe Diabetes and Nutrition Study Group (DNSG) of the EASD has commissioned a systematic review and network meta-analysis of randomized controlled trials of the effect of different intermittent fasting strategies on established cardiometabolic risk factors. The findings generated by this proposed knowledge synthesis will shape guide current guidelines and improve health outcomes by educating healthcare providers and patients, and by guiding future research design.
Conditions
- Obesity
- PreDiabetes
- Diabetes
- Hypertension
- NAFLD
- Metabolic Syndrome
- Dyslipidemias
- Inflammation
- Gout
- Cardiometabolic Syndrome
- Cardiovascular Diseases
Interventions
- DIETARY_SUPPLEMENT
-
Intermittent Fasting
Methods of intermittent fasting strategies, continuous energy restriction, and ad libitum diet.
Sponsors & Collaborators
-
University of Toronto
lead OTHER
Eligibility
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-11-01
- Primary Completion
- 2022-06-30
- Completion
- 2022-08-31
Countries
- Canada
Study Locations
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