Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia, Osteosarcoma, or Non-Hodgkin's Lymphoma
NCT00002738 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2013-03-07
Summary
RATIONALE: Drugs used in chemotherapy, such as trimetrexate glucuronate and leucovorin, use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
PURPOSE: This phase II trial is studying how well combination chemotherapy works in treating children with recurrent acute lymphoblastic leukemia, recurrent osteosarcoma, or refractory non-Hodgkin's lymphoma.
Conditions
Interventions
- DRUG
-
leucovorin calcium
- DRUG
-
trimetrexate glucuronate
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Tanya Trippett, MD · Memorial Sloan Kettering Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Max Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1996-01-31
- Primary Completion
- 2006-06-30
- Completion
- 2006-06-30
Countries
- United States
Study Locations
More Related Trials
-
Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia
NCT00002812 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Children With Lymphoma
NCT00002590 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia
NCT00002744 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy in Treating Children With Very High Risk Acute Lymphocytic Leukemia
NCT00003783 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphocytic Leukemia
NCT00003671 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy and Imatinib Mesylate in Treating Children With Relapsed Acute Lymphoblastic Leukemia
NCT00049569 ·Status: COMPLETED ·Phase: NA
-
Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma
NCT00003650 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma
NCT00003728 ·Status: UNKNOWN ·Phase: PHASE3
-
Combination Chemotherapy in Treating Children With Non-testicular Malignant Germ Cell Tumors
NCT00002489 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia
NCT00002816 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment of Acute Lymphoblastic Leukemia in Children
NCT00165178 ·Status: COMPLETED ·Phase: PHASE3
-
Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma
NCT01403415 ·Status: COMPLETED ·Phase: PHASE1
-
Comparison of Different Combination Chemotherapy Regimens in Treating Infants With Acute Lymphoblastic Leukemia
NCT00015873 ·Status: COMPLETED ·Phase: PHASE3
-
Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors
NCT00024258 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma
NCT00003423 ·Status: UNKNOWN ·Phase: PHASE3
-
Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Neuroblastoma
NCT00017368 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor
NCT00003273 ·Status: WITHDRAWN ·Phase: PHASE2
-
Chemotherapy in Treating Children With Recurrent Acute Myeloid Leukemia
NCT00003178 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Pediatric Patients With Advanced-Stage Large Cell Lymphoma
NCT00002618 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents
NCT03020030 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia
NCT05761171 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic Lymphoma
NCT00004228 ·Status: COMPLETED ·Phase: PHASE3
-
Induction Intensification in Treating Infants With Newly Diagnosed Acute Lymphoblastic Leukemia
NCT00002756 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy in Treating Patients With Retinoblastoma
NCT00002675 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy in Treating Children With Relapsed Acute Leukemia, Acute Myeloid Leukemia, or Blastic Phase Chronic Myelogenous Leukemia
NCT00003735 ·Status: COMPLETED ·Phase: PHASE2