Combination Chemotherapy in Treating Children With Non-testicular Malignant Germ Cell Tumors
NCT00002489 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-06-26
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating children who have non-testicular malignant germ cell tumors.
Conditions
- Extragonadal Germ Cell Tumor
- Ovarian Cancer
Interventions
- BIOLOGICAL
-
dactinomycin
- BIOLOGICAL
- DRUG
- DRUG
- DRUG
-
doxorubicin hydrochloride
- DRUG
-
etoposide
- DRUG
-
leucovorin calcium
- DRUG
-
methotrexate
- DRUG
-
vincristine sulfate
- PROCEDURE
-
conventional surgery
Sponsors & Collaborators
-
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Norma Wollner, MD · Memorial Sloan Kettering Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Max Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1991-10-31
- Primary Completion
- 2002-06-30
- Completion
- 2002-06-30
Countries
- United States
Study Locations
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