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Glycine Supplementation Improves Cognitive Performance in Mexican Older Adults

NCT07643675 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 59

Last updated 2026-06-15

No results posted yet for this study

Summary

The purpose of this study was to evaluate the effects of daily glycine supplementation on metabolic health and cognitive performance in older adults. Over a period of six months, participants received 1,000 mg of glycine per day to determine if this amino acid could improve markers of insulin resistance, glucose metabolism, and cognitive functions such as memory and executive tasks.

The research aimed to identify whether this nutritional intervention provides a safe and effective strategy to support healthy aging, focusing on the link between metabolic balance and brain health in the elderly population.

Conditions

  • Older Adults With Cognitive Decline
  • Insulin Resistance Syndrome
  • Aging

Interventions

DIETARY_SUPPLEMENT

Glycine

Oral supplementation of glycine at a dose of 1,000 mg per day, administered daily over a 6-month period.

Sponsors & Collaborators

  • Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado

    collaborator OTHER_GOV

  • National Polytechnic Institute, Mexico

    collaborator OTHER

  • Brenda Sarahí Beristain Lujano

    lead OTHER

Principal Investigators

  • Brenda Sarahí BS Beristain Lujano, MSc · Escuela Superior de Medicina IPN

Study Design

Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
60 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-12-01
Primary Completion
2025-06-01
Completion
2025-12-01

Countries

  • Mexico

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07643675 on ClinicalTrials.gov