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Effectiveness of Implementing the Adapted Practice Guidelines for Primary Care of Acute Abdomen in Zambia: An Effectiveness-Implementation Hybrid Type 2 Study Design.

NCT07587190 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 280

Last updated 2026-05-14

No results posted yet for this study

Summary

The study aims 1) to adapt, 2) to develop implementation strategies for and 3) to evaluate the effect of implementing a practice guideline for acute abdomen at primary care level in Zambia. We employ a sequential exploratory mixed method study design. Qualitative and quantitative data from health care workers will be used to adapt a practice guideline developed in a high-income into a low- and middle-income (LMIC) context and to develop strategies for successful implementation. The primary outcome of interest is the prospective change in length of stay in hospital among patients presenting with acute abdomen in the intervention site compared to the control site. The study will address the scarcity of literature on practice guidelines for acute abdomen in the LMIC context. The implementation of an adapted guideline may contribute to a reduction of the morbidity and mortality rates associated with acute abdomen in this setting by increasing management capacity at the primary care level.

Conditions

  • Practice Guidelines for Primary Care of Acute Abdomen

Interventions

OTHER

Practice guidelines for primary care of acute abdomen

Adjusted practice guidelines for primary care of acute abdomen will be implemented at the intervention site.

OTHER

No intervention

The control site will receive no intervention.

Sponsors & Collaborators

  • University of Zambia

    collaborator OTHER

  • University of Bergen

    lead OTHER

Principal Investigators

  • Elisabeth Marie Strømme, MD, PhD · University of Bergen

  • Thomas Mildestvedt, MD, PhD · University of Bergen

  • Eivind Meland · University of Bergen

  • Mpundu Makasa · University of Zambia

Study Design

Allocation
NON_RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-09-01
Primary Completion
2026-08-31
Completion
2028-12-31

Countries

  • Zambia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07587190 on ClinicalTrials.gov