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Efficacy of Two Enzyme Cocktails in Healthy Adults

NCT06710392 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 18

Last updated 2026-05-12

No results posted yet for this study

Summary

The goal of this study is to determine the safety and efficacy of two enzyme cocktails in healthy adults with mild to moderate gastrointestinal discomfort. The main question aims to answer whether a 4-week administration of an enzyme cocktail can improve how the participant feels about their gut health. This is done by completing a weekly questionnaire, and the results are compared between the 4 weeks the participants are on a placebo and the 4 weeks the participants are on the enzyme cocktail. Participants will also provide a stool sample at the start and end of each treatment. Stool samples will collected and stored in case further microbiome analysis is warranted.

Conditions

  • Digestive
  • Gastrointestinal Health

Interventions

DIETARY_SUPPLEMENT

Enzyme Cocktail A

Enzyme cocktail A in the form of a capsule with a daily dose of 275mg taken 3 times a day for 4 weeks.

DIETARY_SUPPLEMENT

Enzyme Cocktail B

Enzyme cocktail B in the form of a capsule with a daily dose of 50mg taken 3 times a day for 4 weeks.

DIETARY_SUPPLEMENT

Placebo A

Placebo A matching investigational product A given 3 times a day for 4 weeks.

DIETARY_SUPPLEMENT

Placebo B

Placebo B matching investigational product B given 3 times a day for 4 weeks.

Sponsors & Collaborators

  • University of North Texas, Denton, TX

    collaborator OTHER

  • The Archer-Daniels-Midland Company

    lead INDUSTRY

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-05-29
Primary Completion
2026-02-28
Completion
2026-02-28

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06710392 on ClinicalTrials.gov