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Does Oral Lactate Affect Gut Hormone Secretion in a Dose-response Relationship?

NCT06589856 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2024-09-19

No results posted yet for this study

Summary

To investigate whether there is a linear dose-response relationship between oral lactate and its effects on gut hormone secretion, motility, and appetite.

Hypothesis Oral lactate administration affects gut hormone secretion, insulin levels, motility, appetite sensation and the amount of food intake in a linear dose-response relationship.

Conditions

  • Metabolic Syndrome

Interventions

DIETARY_SUPPLEMENT

Placebo

Placebo (300 mL salt water, NaCl) = CTR

DIETARY_SUPPLEMENT

LAC5

5 g lactate (300 mL lactate drink = 5 g D/L-lactate bound to Na) = LAC5

DIETARY_SUPPLEMENT

LAC10

10 g lactate (300 mL lactate drink = 10 g D/L-lactate bound to Na) = LAC10

DIETARY_SUPPLEMENT

LAC20

20 g lactate (300 mL lactate drink = 20 g D/L-lactate bound to Na) = LAC20

Sponsors & Collaborators

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Esben Sondergaard · Aarhus University, Steno Diabetes Center Aarhus

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-10-31
Primary Completion
2025-01-31
Completion
2025-01-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06589856 on ClinicalTrials.gov