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Fermented Plant-based Portfolio Diet 4 Metabolic Health

NCT06587958 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 89

Last updated 2026-03-19

No results posted yet for this study

Summary

The primary objective of this study is to evaluate the metabolic effects of a high-fiber portfolio diet based on fermented plant-based foods compared to a corresponding non-fermented plant-based diet and a control diet (habitual diet). This will be assessed across gut microbiome profiles (high/low Prevotella), focusing on cardiometabolic risk factors, particularly inflammation.

A total of 100 men and women who meet all inclusion criteria and none of the exclusion criteria will be invited to participate. The study will employ a three-way randomized, controlled cross-over design, featuring six-week interventions separated by six-week washout periods. Participants will attend the clinic on 15 occasions, including screening visits.

Conditions

  • Metabolic Cardiovascular Syndrome

Interventions

DIETARY_SUPPLEMENT

Fermented plant-based foods

Participants will daily consume five different types of fermented plant-based foods, in addition to their habitual diet.

DIETARY_SUPPLEMENT

Non-fermented plant-based foods

Participants will daily consume five different types of non-fermented plant-based foods, in addition to their habitual diet.

OTHER

Habitual diet

Participants will follow their habitual diet.

Sponsors & Collaborators

  • KU Leuven

    collaborator OTHER

  • Göteborg University

    collaborator OTHER

  • Chalmers University of Technology

    lead OTHER

Principal Investigators

  • Rikard Landberg, PhD · Chalmers Univeristy of Technology

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-10-28
Primary Completion
2025-12-18
Completion
2025-12-19

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06587958 on ClinicalTrials.gov