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Spices for Cultivating a Healthy Gut Microbiome and Cardiometabolic Profile

NCT06313580 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2024-03-20

No results posted yet for this study

Summary

Among food products receiving attention for prebiotic functionality, spices represent a flavorful vehicle for cultivating a healthy gut microbiota. As the required doses of spice-derived polyphenols to elicit prebiotic and systemic metabolic effects are not well-characterized, additional research is warranted. Thus, the investigators propose to use a food-first synbiotic (prebiotic + probiotic) approach to examine alterations in the gut microbiota pre- and post-intervention/placebo and their relationship with systemic cardiometabolic effects mediated by short chain fatty acids (SCFA) and gut-derived metabolites.

Conditions

  • Cardiometabolic Syndrome

Interventions

OTHER

Yogurt with added Spices

Consumption of twice daily yogurt with added spices for four weeks.

OTHER

Yogurt without added Spices

Consumption of twice daily yogurt without added spices for four weeks.

Sponsors & Collaborators

  • McCormick Science Institute

    collaborator INDUSTRY

  • University of Alabama, Tuscaloosa

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
50 Years
Max Age
69 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-01
Primary Completion
2024-12-31
Completion
2025-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06313580 on ClinicalTrials.gov