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Food-specific IgG4-guided Elimination Diets Improve Allergy Symptoms in Children

NCT06063044 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 407

Last updated 2023-10-18

No results posted yet for this study

Summary

Allergic diseases in children are major public health concerns due to their widespread and rising prevalence. The most classic pathway to trigger allergy is type I allergy mediated by immunoglobulin E(IgE), but the role of immunoglobulin G4(IgG4) in allergic diseases is still worth exploring.we have collected the data of allergic patients aged 0-14 years for retrospective cross-sectional analysis to evaluate the positive rates of total IgE, HDM IgE, FS-IgE and FS-IgG4. Meanwhile, investigators screened out patients who were treated with FS-IgG4-guided elimination diets with/without probiotics for more than 3 months to clarify the role of FS-IgG4 in childhood allergic diseases by assessing the improvement of clinical symptoms before and after treatment.

Conditions

  • Rhinitis, Allergic
  • Asthma, Allergic
  • Conjunctivitis, Allergic
  • Atopic Dermatitis
  • Chronic Urticaria

Sponsors & Collaborators

  • Second Affiliated Hospital, School of Medicine, Zhejiang University

    lead OTHER

Principal Investigators

  • Huiying Wang · 2nd Affiliated Hospital, School of Medicine, Zhejiang University, China

Eligibility

Min Age
8 Months
Max Age
14 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-01
Primary Completion
2020-12-31
Completion
2020-12-31

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06063044 on ClinicalTrials.gov