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Non-Immunoglobulin E-mediated Food Allergies in Children

NCT04462978 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2022-03-11

No results posted yet for this study

Summary

Non-IgE-mediated gastrointestinal food allergies (non-IgE-GIFA) are an evolving web of clinical conditions characterized by subacute and/or chronic symptoms and include food protein-induced enterocolitis syndrome (FPIES), food protein-induced enteropathy (FPE), food protein-induced allergic proctocolitis (FPIAP), and food protein-induced allergic dysmotility disorders (gastroesophageal reflux disease (GERD), colic and constipation) (FPIMD).

Despite the prevalence and clinical impact of these conditions, the pathogenesis as well as the natural history and the best management of these disorders are still poorly defined. These limitations could be responsible for diagnostic delays and errors, and suboptimal clinical management. We aim to evaluate clinical features, natural course and pathophysiology of non-IgE-GIFA in the pediatric age.

Conditions

  • Non IgE Mediated Food Allergy
  • Food Protein-Induced Enteropathy
  • Food Protein-Induced Proctocolitis
  • Food Protein-Induced Enterocolitis Syndrome
  • Food Protein-induced Motility Disorders

Interventions

OTHER

Non IgE-mediated food allergy

Sponsors & Collaborators

  • Federico II University

    lead OTHER

Eligibility

Min Age
1 Day
Max Age
14 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-01-01
Primary Completion
2023-12-30
Completion
2025-12-28

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04462978 on ClinicalTrials.gov