MedTrace Logo

Effect of the Intake of Corbella Extra Virgin Olive Oil on the Microbiota-gut-brain Axis in Healthy Adults (HEVOOC)

NCT05898113 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-04-01

No results posted yet for this study

Summary

The consumption of the improved extra virgin olive oil (EVOO) of the Corbella variety could have a beneficial effect on the microbiota-intestine-brain axis (MGBA). Olive oil contains polyphenols that are not present in other oils, notably oleocanthal and oleacein, which behave similarly to ibuprofen and have a protective effect on some neurodegenerative diseases. The polyphenols of the oil present prebiotic characteristics, at the level of the intestinal microbiota, which metabolizes them forming bioactive metabolites that can have a modulating effect on the MGBA, improving brain health. In this study, the researchers seek to identify the benefits of the consumption of Corbella variety EVOO on MGBA in healthy participants. The overall benefit of the study would be to achieve knowledge that would allow its future applicability to prevent and improve certain diseases and in general contribute to optimal health.

Conditions

  • Healthy Nutrition

Interventions

OTHER

EXTRA VIRGIN OLIVE OIL

Participants will consume a daily amount of extra virgin olive oil. Can consume the oil either raw or cooked

OTHER

OLIVE OIL LOW POLYPHENOL

Participants will consume a daily amount of olive oil low polyphenol. Can consume the oil either raw or cooked

Sponsors & Collaborators

  • Hospital Clinic of Barcelona

    collaborator OTHER

  • Institut d'Investigacions Biomèdiques August Pi i Sunyer

    collaborator OTHER

  • University of Barcelona

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-06-19
Primary Completion
2023-08-10
Completion
2023-11-24

Countries

  • Spain

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05898113 on ClinicalTrials.gov