MedTrace Logo

Lactate Profile and Fat Oxidation During Exercise

NCT05703100 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 19

Last updated 2023-09-13

No results posted yet for this study

Summary

The goal of this clinical trial is to test whether changes in lactate kinetics during exercise (due to glycogen depletion or hyperthermia) alter the pattern of fat oxidation during a maximal incremental cycle ergometer test in healthy young active people. The main questions it aims to answer are:

* Will a rightward shift in lactate kinetics, induced by a previous glycogen depletion, produce a rightward shift in fat oxidation?
* Will a leftward shift in lactate kinetics due to an increase in ambient temperature produce a leftward shift in fat oxidation?

Participants will perform three maximal incremental tests in three different conditions:

* one in the control condition;
* one with glycogen depletion;
* and one with ambient heat (the latter two in randomized, counterbalanced order).

Conditions

  • Energy Metabolism

Interventions

OTHER

Incremental exercise test

Maximal incremental exercise test on a cycle ergometer (5 min warm-up at 30W, and subsequent steps of 3 min with power increases of 30W)

OTHER

Incremental exercise test under hyperthermia

Maximal incremental exercise test on a cycle ergometer (5 min warm-up at 30W, and subsequent steps of 3 min with power increases of 30W) performed at a room temperature of 35-38ºC (degrees Celsius).

OTHER

Incremental exercise test under glycogen depletion

Maximal incremental exercise test on a cycle ergometer (5 min warm-up at 30W, and subsequent steps of 3 min with power increases of 30W) under glycogen depletion by performing an exercise protocol to deplete glycogen stores plus a low-carbohydrate diet 24 h before incremental testing

Sponsors & Collaborators

  • Technical University of Madrid

    lead OTHER

Principal Investigators

  • Rocío Cupeiro, PhD · Universidad Politecnica de Madrid

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-28
Primary Completion
2023-05-11
Completion
2023-05-11

Countries

  • Spain

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05703100 on ClinicalTrials.gov