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Hyperglycemia and Exercise.

NCT03284216 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2018-12-11

No results posted yet for this study

Summary

This study will determine whether exposure to short-term high blood glucose levels impairs exercise-induced adaptations in glucose tolerance, and whether the pattern of high blood glucose levels plays a role.

Conditions

  • Aerobic Exercise
  • Hyperglycemia
  • Glucose Metabolism Disorders (Including Diabetes Mellitus)

Interventions

PROCEDURE

Steady-state hyperglycemia

Experimental "diabetic like" steady-state hyperglycemia will be induced via a continuous-rate intravenous glucose infusion.

PROCEDURE

Fluctuating hyperglycemia

Experimental "diabetic like" fluctuating hyperglycemia will be induced via repeated intravenous glucose injections.

BEHAVIORAL

Exercise

Moderate-intensity exercise bout (45-minutes of cycling at 70% of their heart rate max) at T=4.5 hours

Sponsors & Collaborators

  • University of Birmingham

    lead OTHER

Principal Investigators

  • Thomas P Solomon, PhD · University of Birmingham

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-08-01
Primary Completion
2018-11-30
Completion
2018-12-08

Countries

  • United Kingdom

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03284216 on ClinicalTrials.gov