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Medium Chain Triglycerides and Aerobic Exercise on Ketone Production in Women With or Without Prediabetes

NCT02678390 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2020-04-07

Study results available
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Summary

The aim of this study is to compare the effect on ketone production of dietary an MCT supplement combined or not with physical exercise in two groups of women (N=10/group), healthy adults and patients with prediabetes. After an evaluation of the metabolism (a 4-hour visit with multiple blood samples) at the beginning of the study, all the participants are taken for one-week the MCT supplement alone follow by a one-week period of taking the MCT supplement in combination with physical exercise. At the end of each period of time, the 4-hour visit for the evaluation of the metabolism is repeated.

Conditions

  • Prediabetic State

Interventions

DIETARY_SUPPLEMENT

MCT

A 5 day consecutive MCT intake of 30 g/day.

DIETARY_SUPPLEMENT

MCT+ aerobic exercise

A 5 day consecutive MCT intake of 30 g/day in combinaison with 30 minutes of aerobic exercise (70% to 80% HRR) per day for the five days.

DIETARY_SUPPLEMENT

Aerobic exercise

A single period of 30 minutes of aerobic exercise (70% to 80% HRR).

DIETARY_SUPPLEMENT

Control day

No MCT or aerobic exercise

Sponsors & Collaborators

  • Université de Sherbrooke

    lead OTHER

Principal Investigators

  • Stephen Cunnane, PhD · Research Centre on Aging, CIUSSS de l'Estrie-CHUS

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
60 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2017-09-30
Completion
2017-09-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02678390 on ClinicalTrials.gov