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Long Term Effects of Different Dietary Protocols on Determinants of Health in Patients' Lymphocytes

NCT05377164 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 12

Last updated 2023-03-01

No results posted yet for this study

Summary

Food choices and eating habits play an important role in the management of common noncommunicable diseases, i.e. diabetes type II, hypertension, metabolic syndrome and others. However, for many popular diets there is yet no consensus on their actual ability to exert health effects and, regardless of some promising results, the underlying molecular mechanisms are not entirely clear. FTIR analysis could provide interesting new information; we therefore propose the analysis of lymphocytes isolated from the peripheral blood of participants who had been on vegan, ketogenic or normal mixed diet for at least one year. In particular we plan to monitor differences in lipid peroxidation, membrane permeability, protein synthesis and DNA damage. All these parameters are important in the development of the above mentioned diseases and were previously shown to be detectable by FTIR. The results will contribute importantly to the understanding of the long-term effects of the respective lifestyle and will allow the formulation of better dietary recommendations to the public.

Conditions

  • Asymptomatic Condition

Interventions

BEHAVIORAL

food choices

Analysis of lymphocytes isolated from the peripheral blood of participants who had been on vegetarian, ketogenic or normal mixed diet for at least one year will be performed.

Sponsors & Collaborators

  • Elettra Synchrotron Trieste

    collaborator UNKNOWN

  • University of Primorska

    lead OTHER

Principal Investigators

  • Saša Kenig, PhD · University of Primorska Faculty of Health Sciences, Polje 42 SI-6310 Izola

Eligibility

Min Age
20 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-05-20
Primary Completion
2022-08-20
Completion
2022-11-20

Countries

  • Slovenia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05377164 on ClinicalTrials.gov