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Impact of Time-restricted Feeding in NAFLD

NCT05220956 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2023-12-28

No results posted yet for this study

Summary

This is a randomised controlled study of patients with Non-Alcoholic Fatty Liver Disease (NAFLD).

Patients will be trained according to the 10 rules of a healthy nutrition according to the German Association for Nutrition (DGE).

One arm will undergo Time-Restricted Feeding (TRF) for 12 weeks. The control arm is not subject to any time restrictions concerning eating.

It will be investigated whether TRF improves insulin sensitivity, impacts on metabolic inflammation and reduces liver steatosis.

Conditions

  • Fatty Liver Disease
  • Fatty Liver
  • Fatty Liver, Nonalcoholic

Interventions

BEHAVIORAL

Intermittent fasting

One arm will undergo a TRF diet (Time-Restricted Feeding) for 12 weeks while both arms undergo a training according to the 10 rules of healthy nutrition of the DGE.

BEHAVIORAL

DGE diet

The control arm is not a subject to any time restrictions concerning eating while both arms undergo a training according to the 10 rules of healthy nutrition of the DGE.

Sponsors & Collaborators

  • University of Turin, Italy

    collaborator OTHER

  • Johannes Gutenberg University Mainz

    lead OTHER

Principal Investigators

  • Jörn M. Schattenberg, Prof. · 1. Medical Department

Study Design

Allocation
RANDOMIZED
Purpose
SCREENING
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-10-01
Primary Completion
2024-09-01
Completion
2024-12-01

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05220956 on ClinicalTrials.gov