Fatty liver disease, also called hepatic steatosis, is a condition characterized by excess fat accumulation in liver tissue. Many patients are asymptomatic, but disease can progress to steatohepatitis, fibrosis, cirrhosis, and liver cancer in a subset of individuals. Major risk factors include obesity, diabetes, and alcohol use.
A major meta-analysis of 19 randomized trials involving 123,940 participants found that only six side effects are actually caused by statins, challenging long-standing concerns about the drugs' safety profile.
Health and Human Services Secretary Robert F. Kennedy Jr. announced plans to review the safety of ultra-processed foods, criticizing the GRAS exemption that allows companies to verify ingredient safety without FDA oversight since 1997.
Recent studies demonstrate tirzepatide's efficacy extends beyond diabetes management, showing reduced glaucoma risk in diabetic patients and significant improvements in pediatric Type 2 diabetes treatment with superior weight loss outcomes.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07564947 |
Impact of Ganoderma Lucidum on NRF2 Levels and Antioxidant Status in Metabolic Asscociated Fatty Liver Disease (GL-MAFLD-NRF2 Study) |
ENROLLING_BY_INVITATION | NA |
| NCT07530419 |
Samsung S-Viscosity vs Canon Dispersion Slope in Steatotic Liver Disease (SAVID-SLD) |
NOT_YET_RECRUITING | |
| NCT07495332 |
Siemens Biomarker Multi-modality |
RECRUITING | NA |
| NCT07449767 |
Effects of Short-Term Resistance Training on Diaphragm Thickness, Hepatic Fat Density, and Quality of Life in Healthy Older Men |
COMPLETED | NA |
| NCT07399600 |
Personalized Transcranial Magnetic Stimulation (TMS) for Metabolic Dysfunction and Alcohol-Related Liver Disease |
NOT_YET_RECRUITING | NA |
| NCT07362745 |
Single-Cell and Spatial Transcriptomics Analysis of Steatotic Donor Liver Susceptibility to Post-Transplant Injury |
COMPLETED | |
| NCT07242222 |
Erdosteine in the Treatment of Nonalcoholic Fatty Liver Disease |
RECRUITING | PHASE1/PHASE2 |
| NCT07238985 |
Cilostazol in the Treatment of Nonalcoholic Fatty Liver Disease |
RECRUITING | PHASE1/PHASE2 |
| NCT07193082 |
Effect of Inspiratory Muscle Training on Diaphragm Muscle Thickness, Fatty Liver Density and Aerobic Capacity in Elderly Men: A Randomized Controlled Trial |
COMPLETED | NA |
| NCT07068191 |
Gepaktiv vs UDCA and Ademetionine in MAFLD With Hepatomegaly |
RECRUITING | NA |
