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Impact of the Food Matrix on Iodine Bioavailability

NCT04867031 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 13

Last updated 2023-01-10

No results posted yet for this study

Summary

This study is a randomized crossover trial, lasting 12 days in total, which will assess the difference in iodine bioavailability (as a percentage of iodine consumed that is excreted in urine) from three iodine-rich foods; semi-skimmed milk, white fish, and dried seaweed sheets. Each of the three foods will provide approximately 140µg of iodine, and iodine excretion will be monitored for 36 hours following food ingestion via collection and analysis of urine.

Conditions

  • Iodine Bioavailability

Interventions

DIETARY_SUPPLEMENT

Milk

One portion of semi-skimmed cow's milk (approx. 450mL), providing \~140µg of iodine.

DIETARY_SUPPLEMENT

Fish

One portion of cod (approx. 130g), providing \~140µg of iodine.

DIETARY_SUPPLEMENT

Seaweed

One portion of dried seaweed sheets (approx. 6g), providing \~140µg of iodine.

Sponsors & Collaborators

  • British Broadcasting Corporation

    collaborator INDUSTRY

  • University of Glasgow

    lead OTHER

Principal Investigators

  • Emilie Combet, PhD · University of Glasgow

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
48 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-08-26
Primary Completion
2018-07-03
Completion
2018-07-03

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04867031 on ClinicalTrials.gov