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Respiratory Mechanics and Gas Exchange Characteristics in Patient With SARS-CoV-2

NCT04486729 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2020-07-27

No results posted yet for this study

Summary

The combination of different ventilatory strategies and its effects on respiratory mechanics and gas exchange in patients under mechanical ventilation with acute respiratory distress syndrome secondary to coronavirus-19 has been scarcely described.

Conditions

  • Covid19
  • ARDS, Human

Interventions

OTHER

High PEEP with end inspiratory pause

Applying a PEEP value 10 cmH2O higher than the lower inflection point of the pressure-volume curve of the respiratory system with end inspiratory pause addition in volumen control ventilation

OTHER

Low PEEP - FiO2 high

Applying a PEEP value equal to the lower inflection point of the pressure-volume curve of the respiratory system with a FiO2 necessary to achieve a SpO2 96-98%

OTHER

High PEEP without end inspiratory pause

Applying a PEEP value 10 cmH2O higher than the lower inflection point of the pressure-volume curve of the respiratory system without end inspiratory pause addition in volumen control ventilation

OTHER

Low PEEP - FiO2 low

Applying a PEEP value equal to the lower inflection point of the pressure-volume curve of the respiratory system with a FiO2 necessary to achieve a SpO2 88-92%

Sponsors & Collaborators

  • Sanatorio Anchorena San Martin

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-07-01
Primary Completion
2020-10-10
Completion
2020-10-20

Countries

  • Argentina

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04486729 on ClinicalTrials.gov