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Assessment of Lung Mechanics in COVID-19 Acute Respiratory Distress Syndrome

NCT04597853 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 25

Last updated 2021-05-10

No results posted yet for this study

Summary

This study is meant to assess the lung mechanics in SARS-CoV-2 induced acute respiratory failure. A precise characterisation of lung mechanics and heart-lung-interactions might allow a better understanding of SARS-CoV-2 induced acute respiratory failure and thus lead to better mechanical ventilation strategies.

This monocentric, observational study of critically ill COVID-19 patients in the ICU, will employ impedance tomography, right-heart catheterization, oesophageal pressure measurements, indirect calorimetry as well as classic mechanical ventilation parameters to characterise the mechanical characteristics of the lung as well as the heart-lung interactions in SARS-CoV-2 induced acute respiratory failure.

Conditions

  • Covid19
  • ARDS

Interventions

DIAGNOSTIC_TEST

Assessment of lung mechanics and heart-lung interactions

Impedance tomography, right-heart catheterization, oesophageal pressure measurements, indirect calorimetry and classic mechanical ventilation parameters

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Philipp K Buehler, MD · Institute of Intensive Care Medicine, University Hospital Zurich

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-01
Primary Completion
2021-12-31
Completion
2022-03-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04597853 on ClinicalTrials.gov