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Different PEEP Settings of COVID-19 Induced ARDS

NCT04359251 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2020-04-24

No results posted yet for this study

Summary

This was a multi-center prospective study. All consecutive severe cases of COVID-19 whose PO2/FiO2\<300mmHg with invasive ventilation admitted to 5 fixed-point receive COVID-19 patients hospitals in Wuhan from 5 March to 15 March 2020 were included. Epidemiological, clinical data, lung mechanics, artery blood gas test and hemodynamics at three methods to titrate PEEP, optimizing oxygenation, optimizing compliance, ARDSnet. The study was approved by the Ethics Committee of Zhongda Hsopital, Southeast University.

Conditions

  • COVID-19
  • Mechanical Ventilation Pressure High
  • Acute Respiratory Distress Syndrome

Interventions

OTHER

Gas exchanges at different PEEP

Gas exchanges measurement at different PEEP

OTHER

lung mechanics at different PEEP

lung mechanics measurement at different PEEP

OTHER

Hemodynamics changes at different PEEP

Hemodynamics changes measurement at different PEEP

Sponsors & Collaborators

  • Southeast University, China

    lead OTHER

Principal Investigators

  • Chun C Pan · Zhongda hospital, Southeast University, Jiangsu, China

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-03-05
Primary Completion
2020-03-25
Completion
2020-03-25

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04359251 on ClinicalTrials.gov