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Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface

NCT04198740 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2026-04-27

No results posted yet for this study

Summary

This study aims to obtain the lacrimal fingerprint for frequent pathologies of the ocular surface and establish a normative base for each of them.

Conditions

  • Dry Eye Syndrome
  • Infectious Keratoconjunctivitis
  • Mucous Membrane Pemphigoid
  • Allergic Conjunctivitis

Interventions

DIAGNOSTIC_TEST

Tear sample collection via Schirmer strip and subsequent analysis by mass spectrometry

During regular consultations at the ophthalmology department of the CHUM, eligible patients will undergo a standard 5 minute Schirmer tear test. The Schirmer strips will serve as tear samples and will be sent to UQAM's Department of chemistry for mass spectrometry analysis.

Sponsors & Collaborators

  • Université du Québec a Montréal

    collaborator OTHER

  • Centre hospitalier de l'Université de Montréal (CHUM)

    lead OTHER

Principal Investigators

  • Marie-Claude Robert, MD, M.Sc · Centre hospitalier de l'Université de Montréal (CHUM)

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-02-01
Primary Completion
2034-10-31
Completion
2035-01-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04198740 on ClinicalTrials.gov