MedTrace Logo

Dry Eye Evaluation System Based on Bioinformatics

NCT04109170 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2019-09-30

No results posted yet for this study

Summary

Dry eye is a common ocular surface disease of multifactorial etiology characterized by elevated tear osmolality and inflammation leading to a disrupted ocular surface. The latter is a risk factor for ocular surface infection, yet overt infection is not commonly seen clinically in the typical dry eye patient. This suggests that important innate mechanisms operate to protect the dry eye from invading pathogens. Understand the pathogenesis of dry eye will be the measure to prevention and treatment of dry eye.

In this essay, the investigators use the data of experiment in the patients with dry eye and normal, acquire their tear production, tear film stability, and surface damage. The investigators use weka to calculate the prediction accuracy of the 6 algorithm and select the best one, optimize the parameters to get the final prediction accuracy.

Conditions

  • Dry Eye

Sponsors & Collaborators

  • Huaxia Eye Hospital Group

    lead OTHER

Principal Investigators

  • Chi Zhang, PhD,MD · Huaxia Eye Hospital of Foshan

Eligibility

Min Age
10 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-09-23
Primary Completion
2019-12-23
Completion
2020-01-23

Countries

  • China

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04109170 on ClinicalTrials.gov