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Ocular Surface Immune Response in Dry Eye Disease

NCT02042820 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 67

Last updated 2017-10-18

No results posted yet for this study

Summary

In vivo confocal microscopy (IVCM) is a sensitive imaging tool for detecting dry eye-associated subclinical inflammation. Studies have previously shown that IVCM provides an in vivo metric to measure inflammatory changes in the central cornea. The objective of the current study is to assess inflammatory response changes in the peripheral cornea and the conjunctiva by analyzing epithelial immune cell density and morphology in these areas and then correlating the IVCM findings to clinical signs and symptoms to establish novel objective imaging biomarkers.

Conditions

Interventions

OTHER

In vivo confocal microscopy (IVCM)

IVCM is a sensitive tool for detecting dry eye-associated subclinical inflammation.

Sponsors & Collaborators

  • Tufts Medical Center

    lead OTHER

Principal Investigators

  • Pedram Hamrah, MD · MEEI

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-01-31
Primary Completion
2015-07-31
Completion
2015-07-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02042820 on ClinicalTrials.gov