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Point of Care Testing of Inflammatory Markers in Tears

NCT02315079 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 63

Last updated 2019-07-24

No results posted yet for this study

Summary

To evaluate the use of a point of care device to measure markers of inflammation in various eye conditions. In particular, matrix metalloproteinase-9 (MMP-9) will be measured. MMP-9 is an enzyme that plays a role in inflammation. The value obtained with the point of care device will be correlated with values obtained using gel electrophoresis to measure MMP-9 from the same sample. These data will be compared to clinical exam findings and questionnaires to help the investigators better understand the role of this marker of inflammation in eye diseases and possibly improve diagnostic abilities.

Conditions

  • Dry Eye Syndrome

Interventions

OTHER

Eye inflammation

This group will have a regular eye exam with the collection of tears. In addition, a the Ocular Surface Disability Index Survey of National Eye Institute Visual Functioning Questionnaire- 25 may be administered.

OTHER

Without eye inflammation

This group will have a regular eye exam with the collection of tears.

Sponsors & Collaborators

  • University of Florida

    lead OTHER

Principal Investigators

  • Sonal Tuli, MD · University of Florida, Department of Ophthalmology

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2017-01-31
Completion
2017-01-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02315079 on ClinicalTrials.gov