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The Role of Cytokines and Mast Cell in the Pathogenesis of SLK, Conjunctivochalasis, and Dry Eye

NCT02160327 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 105

Last updated 2014-06-24

No results posted yet for this study

Summary

The specific aims of the the investigators studies are as follows:

* To collect the tear samples from patients with different ocular surface disorders, including SLK, conjunctivochalasis, and keratoconjunctivitis sicca (KCS).
* To evaluate the differential expression of tear cytokines and pH values between different ocular surface disorders.
* To collect the surgical conjunctival specimens from the patients with SLK and conjunctivochalasis.
* To evaluate the factors inducing mast cell migration and how mast cell is activated in SLK via surgical specimens and cultivated fibroblast.

Conditions

  • Superior Limbic Keratoconjunctivitis
  • Conjunctivochalasis
  • Dry Eye

Sponsors & Collaborators

  • National Taiwan University Hospital

    lead OTHER

Principal Investigators

  • Fung-Rong Hu, MD · National Taiwan University Hospital

Eligibility

Min Age
20 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-03-31
Primary Completion
2017-12-31
Completion
2017-12-31

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02160327 on ClinicalTrials.gov