Ocular Surface Disease in Chronic Graft-Versus-Host Disease (GVHD) Patients
NCT02712762 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 5
Last updated 2024-04-17
Summary
This study aims to profile the ocular surface inflammation of chronic Graft-Versus-Host Disease patients by investigating conjunctival cells, and clinical imaging for conjunctival redness and tear stability. Hence, the investigators expect to find an increased in inflammatory cell population in GVHD conjunctival samples.
Conditions
- Dry Eye
- GVHD
Interventions
- OTHER
-
Cross-sectional study
Sponsors & Collaborators
-
Singapore General Hospital
collaborator OTHER -
Singapore National Eye Centre
lead OTHER_GOV
Eligibility
- Min Age
- 21 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-06-30
- Primary Completion
- 2020-11-30
- Completion
- 2020-11-30
Countries
- Singapore
Study Locations
More Related Trials
-
Ocular Surface Immune Response in Dry Eye Disease
NCT02042820 ·Status: COMPLETED
-
Influencing Factors on Dry Eye Syndrome and Ocular Surface Disease
NCT03364322 ·Status: COMPLETED
-
Ikervis for DED Due to GVHD Post Allo-HSCT
NCT04636918 ·Status: UNKNOWN ·Phase: PHASE4
-
Comparing the Quality of Topical Autologous Serum in Different Etiologies of Dry Eye Syndrome
NCT02774707 ·Status: UNKNOWN
-
Efficacy and Safety of SJP-0132 Eye Drops in Chinese Patients With Dry Eye Disease
NCT06717152 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluating Patients With Eye Allergies and Determining if There Are Also Dry Eyes
NCT01679015 ·Status: COMPLETED
-
Cyclosporine Implant for Ocular Graft-Versus-Host Disease
NCT00102583 ·Status: COMPLETED ·Phase: PHASE1
-
Ocular Surface Dry Eye Microbiome
NCT02306668 ·Status: UNKNOWN
-
Evaluation of 0.05% CsA and 0.1% FK506 Eye Drops in Ocular GVHD Treatment
NCT05294666 ·Status: COMPLETED ·Phase: PHASE4
-
Ocular Micro-vascular Research Base on Functional Slip Lamp Biomicroscopy
NCT03747614 ·Status: UNKNOWN ·Phase: PHASE4
-
Dry Eye Evaluation System Based on Bioinformatics
NCT04109170 ·Status: UNKNOWN
-
Exploring Immune Cell Signatures in Autoimmunity and Dry Eye Syndrome
NCT02715323 ·Status: COMPLETED
-
Collection of Ocular Surface Impressions Cytology of the Living Eye From Patients With Dry Eyes or Limbal Stem Cell Deficiency.
NCT06255301 ·Status: COMPLETED
-
Safety and Efficacy of Topical Tacrolimus 0.05% in the Treatment of Ocular Graft-Versus-Host Disease
NCT01977781 ·Status: COMPLETED ·Phase: PHASE1
-
Clinical Feature and Treatment of Microsporidial Keratoconjunctivitis
NCT03555409 ·Status: UNKNOWN
-
The Pathogenesis of Superior Limbic Keratoconjunctivitis
NCT00167050 ·Status: UNKNOWN
-
The Effects and Safety of 5% Lifitegrast Ophthalmic Solution in Subjects With Dry Eye Disease in Ocular Graft-versus-Host Disease
NCT04792580 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Preliminary Clinical Study of the Effectiveness and Safety of Ocular Surface Microbiota Transplantation in the Treatment of Dry Eye Disease
NCT07298811 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Microbiological Diagnosis of Infectious Keratitis to Pathogenic Fastidious Germs
NCT02819232 ·Status: COMPLETED ·Phase: NA
-
Autologous Plasma Treatment for Severe Dry Eye Patients
NCT03768115 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
Effect of SHR8058 on Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction
NCT05515471 ·Status: COMPLETED ·Phase: PHASE3
-
Brimonidine Eye Drops for Treatment of Ocular Graft-vs-Host Disease (oGVHD)
NCT02975557 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Treatment of Ocular Graft-versus-Host Disease (GVHD) With Topical Loteprednol Etabonate 0.5%
NCT01695668 ·Status: COMPLETED ·Phase: NA
-
Changes of Inflammatory Cytokines in the Tears of Moderate and Severe MGD Treated With Topical Loteprednol Etabonate
NCT01692652 ·Status: COMPLETED ·Phase: NA
-
The Ocular Microbiome in Patients With Dry Eye Disease
NCT04656197 ·Status: COMPLETED