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Cardiovascular Health Arterial Stiffness Raspberry and Microbiome (CHARM)

NCT04087278 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 79

Last updated 2023-11-01

No results posted yet for this study

Summary

In this study, the investigators aim to determine the health benefits of red raspberry ellagitannin consumption on cardiovascular health. The study population is stratified according to the urolithin metabotypes (gut-microbial metabolic profile): UM-0, UM-A and UM-B.

The investigators will evaluate changes in blood pressure, endothelial function, arterial stiffness, lipid profile, cognitive performance and gut microbiome composition.

Conditions

  • Healthy Volunteers

Interventions

DIETARY_SUPPLEMENT

Red Raspberry Ellagitannin Extract

Purified red raspberries ellagitannins extract 560 mg (4 capsules/day)

DIETARY_SUPPLEMENT

Matching Placebo

Placebo treatment matching intervention (no ellagitannin) 560 mg (4 capsules/day)

Sponsors & Collaborators

  • Centro de Edafología y Biología Aplicada del Segura

    collaborator OTHER_GOV

  • Washington Red Raspberry Commission

    collaborator OTHER

  • King's College London

    lead OTHER

Principal Investigators

  • Ana Rodriguez-Mateos, PhD · King's College London

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-09-19
Primary Completion
2023-03-14
Completion
2023-03-14

Countries

  • United Kingdom

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04087278 on ClinicalTrials.gov