Biological Effects of Quercetin in COPD
NCT03989271 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 29
Last updated 2023-08-16
Summary
This study determines whether quercetin supplementation reduces the inflammation and oxidative stress markers in patients with chronic obstructive pulmonary disease. It is small study with 8 subjects receive quercetin 2000 mg/day and 4 subjects receive placebo.
Conditions
Interventions
- DRUG
-
Quercetin
Placebo
Sponsors & Collaborators
-
National Institutes of Health (NIH)
collaborator NIH -
Quercegen Pharmaceuticals
collaborator INDUSTRY -
National Center for Complementary and Integrative Health (NCCIH)
collaborator NIH -
Temple University
lead OTHER
Principal Investigators
-
Nathaniel Marchetti, D.O. · Temple University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-10-01
- Primary Completion
- 2024-05-30
- Completion
- 2025-07-01
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Palmitic Acid and Human Microvascular Function
NCT06683534 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Effect of Quercetin on Prophylaxis and Treatment of COVID-19
NCT04377789 ·Status: COMPLETED ·Phase: NA
-
Study to Investigate the Clinical Benefits of Dietary Supplement Quercetin for Managing Early Mild Symptoms of COVID-19
NCT04861298 ·Status: COMPLETED ·Phase: NA
-
Effects of Quercetin on Metabolic Health
NCT05297032 ·Status: TERMINATED ·Phase: NA
-
A 2 Week, Crossover Trial of Dietary Nitrate in Chronic Obstructive Pulmonary Disease
NCT02521532 ·Status: COMPLETED ·Phase: NA
-
The Effect of Quercetin in Sarcoidosis
NCT00402623 ·Status: COMPLETED ·Phase: NA
-
The Effectiveness of Phytotherapy in SARS-COV2(COVID-19)
NCT04851821 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Biological Effects of a Polyphenol Supplement
NCT05829382 ·Status: COMPLETED ·Phase: NA
-
Impact of Cocoa Flavanols on Pulmonary Oxygen Uptake Kinetics and Exercise Tolerance in Sedentary Middle-aged Adults
NCT04370353 ·Status: COMPLETED ·Phase: NA
-
Modulation of Cerebral Blood Flow Using Quercetin, a Nutritional Supplement
NCT01376011 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Effect of a Single Dose of Cranberry Beverage on Inflammation and Oxidative Stress
NCT01780922 ·Status: COMPLETED ·Phase: NA
-
Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease
NCT03943459 ·Status: UNKNOWN ·Phase: PHASE3
-
Effect of Chronic Consumption of a Cranberry Beverage on Inflammation and Oxidative Stress
NCT01527617 ·Status: COMPLETED ·Phase: NA
-
Study on the Effects of Epicatechin and Quercetin Supplementation on Vascular Function and Blood Pressure (FLAVO)
NCT01691404 ·Status: COMPLETED ·Phase: NA
-
Effects of a Polyphenol-rich Cranberry Extract on Cardiometabolic and Neurocognitive Health
NCT05062954 ·Status: UNKNOWN ·Phase: NA
-
Flavonoids, Blood Pressure and Blood Vessel Function
NCT01530893 ·Status: COMPLETED ·Phase: NA
-
Quercetin in Coronary Artery By-pass Surgery
NCT04907253 ·Status: COMPLETED ·Phase: PHASE2
-
The Effects of Walnuts on Antioxidant Capacity and Nutritional Status in Humans
NCT00626691 ·Status: COMPLETED ·Phase: NA
-
Study on Whether Tart Cherry Juice Can Reduce Oxidative Stress and Inflammation
NCT00847743 ·Status: COMPLETED ·Phase: NA
-
Effect of Polyphenol Extract on Cardiovascular Health Markers: a 4 Way Randomised Crossover Study
NCT05220059 ·Status: UNKNOWN ·Phase: NA
-
L-carnitine and Coenzyme Q10 in Relation to the Oxidative Stress, Antioxidant Enzymes Activities, Inflammation, and the Risk of Coronary Artery Disease
NCT01819701 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Effects of a Brown Seaweed Tart Cherry Blend in Mild-moderate Hypertension
NCT06559982 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Investigation of the Acute Effect of Novel Olive Oil on Postprandial Oxidative Stress Biomarkers (BioliveCT)
NCT05771571 ·Status: COMPLETED ·Phase: NA
-
Effects of Antioxidants on Cardiovascular Risk Measures (Spice Study)
NCT00954902 ·Status: COMPLETED ·Phase: NA
-
Effect of Antioxidant Intake on Cardiovascular Risk
NCT01964846 ·Status: COMPLETED ·Phase: NA