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Effects of Quercetin on Metabolic Health

NCT05297032 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 5

Last updated 2023-01-10

No results posted yet for this study

Summary

Quercetin is a natural flavonoid compound widely found in vegetables, fruits, and nuts. It has a long history of use as a dietary supplement. This study aims to assess results from a computational model suggesting that quercetin may offer novel benefits to metabolic health. Participants will take quercetin (as Quercetin Phytosome, a proprietary formulation with enhanced absorption properties) for 90 days while keeping lifestyle habits consistent throughout to estimate net effects of quercetin as much as possible. Blood samples will be collected at the beginning and end of the study to assess the effects of quercetin supplementation on metabolic health metrics such as LDL cholesterol, blood sugar, liver, kidney and immune function and calculated metabolic age. In addition, questionnaires will be completed to ensure compliance with study requirements and assess potential quercetin benefits in the participants' quality of life. This work will provide a proof-of-concept from a computational model of nutraceutical compounds and proposes a new application of quercetin in support of healthy human metabolism.

Conditions

  • Quercetin
  • Lipid Metabolism
  • Aging

Interventions

DIETARY_SUPPLEMENT

Quercetin Phytosome

All participants will ingest 1 capsule of Quercetin Phytosome (250 mg) three times daily with meals for 90 days.

Sponsors & Collaborators

  • Indena S.p.A

    collaborator INDUSTRY

  • Thorne HealthTech, Inc

    lead INDUSTRY

Principal Investigators

  • Stephen Phipps, ND, PhD · Thorne HealthTech, Inc

  • Loukia Lili, PhD · Thorne HealthTech, Inc

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
20 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-03-24
Primary Completion
2022-08-31
Completion
2022-09-02

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05297032 on ClinicalTrials.gov