Palmitic Acid and Human Microvascular Function
NCT06683534 · Status: NOT_YET_RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2026-04-29
Summary
The goal of this study is to learn how a supplement Quercetin can affect microvascular function.
Participants will:
* give two blood draws of 5 mL each
* have a camera placed under the tongue to take pictures of blood vessels
* have 2 laser Doppler microdialysis catheters placed on the forearm to monitor blood vessels before and after local drug infusion
Researchers will compare blood vessel function of those who take estrogen supplements to those who do not.
Conditions
- Microvascular Dysfunction
- Microvasculature
- Cardiovascular Diseases
- Cardiovascular Diseases (CVD)
- Microvascular Health
- Obesity and Overweight
Interventions
- DIETARY_SUPPLEMENT
-
Quercetin (dietary supplement)
Quercetin will be provided to take one Quercetin per day for 30 days to look for differences in microvascular function.
- DRUG
-
Subjects randomized to receive placebo will be administered a standard placebo sugar pill.
Sponsors & Collaborators
-
Medical College of Wisconsin
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-07-31
- Primary Completion
- 2030-12-31
- Completion
- 2030-12-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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