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Adverse Neurogenic Actions of Dietary Salt

NCT02881515 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 77

Last updated 2023-03-23

No results posted yet for this study

Summary

Excess dietary salt increases the risk for cardiovascular events, even in people that are not hypertensive. There is some evidence that excess dietary salt exaggerates blood pressure and sympathetic nervous system responses to various perturbations and increases blood pressure variability. This proposal will examine the effects of low, medium, and high salt diets on cardiovascular reactivity and blood pressure variability.

Conditions

  • Blood Pressure

Interventions

OTHER

Low Sodium Diet

Ten days of low sodium diet

OTHER

Medium Sodium Diet

Ten days of a medium sodium diet

OTHER

High Sodium Diet

Ten days of a high sodium diet

Sponsors & Collaborators

  • University of Delaware

    lead OTHER

Principal Investigators

  • William B Farquhar, PhD · University of Delaware

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-04-30
Primary Completion
2022-11-22
Completion
2022-11-22

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02881515 on ClinicalTrials.gov