The Potassium Supplementation Study
NCT05887622 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2026-05-05
Summary
This study will test whether potassium supplementation can reduce the deleterious effect of a high sodium diet on blood vessel function, blood pressure reactivity and autonomic nervous system function in apparently healthy adults.
Conditions
- Cardiovascular Health
- Cardiovascular Risk Factor
Interventions
- DIETARY_SUPPLEMENT
-
Potassium chloride supplement
Subjects will receive 64 mmol of KCl on the high potassium/high sodium condition.
- DIETARY_SUPPLEMENT
-
Placebo
Subjects will receive a placebo capsule on the moderate potassium/low sodium diet and the moderate potassium/high sodium diet
Sponsors & Collaborators
-
University of Delaware
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-01-24
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- United States
Study Locations
More Related Trials
-
Analyzing Genetic Factors Involved in Blood Pressure Changes Due to Salt and Potassium Intake (The GenSalt Study)
NCT00721721 ·Status: COMPLETED ·Phase: PHASE3
-
Dietary Counseling or Potassium Supplement to Increase Potassium Intake in Patients With High Blood Pressure
NCT03809884 ·Status: COMPLETED ·Phase: PHASE3
-
Potassium Intake-response Trial to Control Hypertension
NCT05758142 ·Status: TERMINATED ·Phase: NA
-
Sodium-Potassium Blood Pressure Trial in Children
NCT00000521 ·Status: COMPLETED ·Phase: PHASE4
-
Dietary Salt Intake and Vascular Function
NCT00590512 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Potassium Supplementation in CKD
NCT03253172 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Increasing Potassium Intake in Hypertensive Individuals
NCT02759367 ·Status: COMPLETED ·Phase: NA
-
Vascular Effects of Dietary Salt in Humans With Salt-Resistant Blood Pressure
NCT03424993 ·Status: COMPLETED ·Phase: PHASE4
-
Sodium Lowering Vascular Effects Trial
NCT05388032 ·Status: RECRUITING ·Phase: NA
-
Potassium-Magnesium Citrate as a Blood Pressure Lowering Agent in Hypertensive Patients
NCT01074918 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Central Sodium Sensing: Implications for Blood Pressure Regulation
NCT05480722 ·Status: COMPLETED ·Phase: NA
-
The Effect of Sodium Reduction on Blood Pressure and Physical Function in Older Adults
NCT04074941 ·Status: COMPLETED ·Phase: NA
-
Effects of Acute Dietary Sodium on Cerebrovascular Reactivity and Blood Pressure Reactivity
NCT03564262 ·Status: COMPLETED ·Phase: NA
-
China Salt Substitute Study
NCT00145756 ·Status: COMPLETED ·Phase: NA
-
Adverse Neurogenic Actions of Dietary Salt
NCT02881515 ·Status: COMPLETED ·Phase: NA
-
Vascular Responses to Sympathetic Activation and Altered Shear Rate: The Impact of Hypertension and Sodium Intake
NCT03558022 ·Status: COMPLETED ·Phase: NA
-
Blood Pressure Regulation - Role of Potassium
NCT02380157 ·Status: COMPLETED ·Phase: PHASE4
-
Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension
NCT02653560 ·Status: COMPLETED ·Phase: PHASE4
-
Dietary Nitrates and Vascular Function in Patients With Peripheral Artery Disease
NCT01983826 ·Status: COMPLETED ·Phase: NA
-
Hypertension Prevention Trial (HPT) Feasibility Study
NCT00000501 ·Status: COMPLETED ·Phase: PHASE2
-
Study of the Effects of an Oral Nitric Oxide Supplement on Blood Pressure in Prehypertensive Adults
NCT01937754 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
High Potassium Diet with Spices and Herbs As Salt Substitute for Lowering Blood Pressure in Older Adults: Study Protocol
NCT06683430 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Salt Sensitivity in Young Adults
NCT02588352 ·Status: COMPLETED ·Phase: NA
-
Genetic Epidemiology of Blood Pressure Intervention
NCT00079690 ·Status: COMPLETED
-
Effect of Dietary Sodium Intake on Vascular Endothelium
NCT01550315 ·Status: COMPLETED ·Phase: NA