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fMRI of Hypothalamic Responses to Glucose, Fructose, Sucrose and Sucralose

NCT03247114 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2017-08-11

No results posted yet for this study

Summary

The study will consist of five occasions with one week in between. BOLD signal intensity of the hypothalamus will be measured using fMRI. Measurements will be done before and after drinking 300 ml plain water (reference) or water to which different sweeteners will be added.

Conditions

  • Healthy

Interventions

OTHER

Water

Water, 300 ml at room temperature

OTHER

Glucose

Glucose, 50 grams in 300 ml water at room temperature

OTHER

Fructose

Fructose, 50 grams in 300 ml water at room temperature

OTHER

Sucrose

Sucrose, 50 grams in 300 ml water at room temperature

OTHER

Sucralose

Sucralose, 0.33 grams in 300 ml water at room temperature

Sponsors & Collaborators

  • Leiden University Medical Center

    collaborator OTHER

  • Unilever R&D

    lead INDUSTRY

Principal Investigators

  • Jeroen van der Grond, Dr · Leiden University Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
25 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-02-22
Primary Completion
2015-05-22
Completion
2015-05-22

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03247114 on ClinicalTrials.gov