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The Effects of Sodium and Potassium on Blood Pressure, Vascular Function and Renal Function

NCT01575041 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2025-04-01

No results posted yet for this study

Summary

To determine the effect of (1) increased sodium intake and (2) increased potassium intake on blood pressure, vascular function and renal function in untreated (pre)hypertensive subjects.

Conditions

  • Hypertension
  • Blood Pressure
  • Vascular Function
  • Renal Function

Interventions

DIETARY_SUPPLEMENT

Sodium

Sodium Chloride (provided by Microz, Geleen, Netherlands): 8 capsules per day which equals a sodium intake of 3 grams.

DRUG

Potassium

Potassium Chloride (provided by Microz, Geleen, Netherlands): 8 capsules per day which equals a potassium intake of 3 grams.

DRUG

Placebo

Placebo (cellulose, provided by Microz, Geleen, Netherlands): 8 capsules per day.

Sponsors & Collaborators

  • Top Institute Food and Nutrition

    collaborator OTHER

  • Wageningen University

    lead OTHER

Principal Investigators

  • Johanna M Geleijnse, PhD · Wageningen University, Division of Human Nutrition

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
40 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-01-31
Primary Completion
2012-07-31
Completion
2012-08-31

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01575041 on ClinicalTrials.gov