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Ketamine and Kidney Injury in Cardiac Surgery

NCT05268562 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 200

Last updated 2025-10-07

No results posted yet for this study

Summary

The purpose of this study is to investigate the affects of ketamine use for anesthesia at the beginning of heart surgery on kidneys compared to the use of propofol.

Conditions

  • Cardiac Surgery

Interventions

DRUG

Ketamine

1-2 mg/kg induction with additional medication administered as needed to achieve intubating conditions

DRUG

Propofol

0.5-1 mg/kg induction with additional medication administered as needed to achieve intubating conditions

Sponsors & Collaborators

Principal Investigators

  • Erica D Wittwer, MD, PhD · Mayo Clinic

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-02
Primary Completion
2025-09-05
Completion
2026-06-30
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05268562 on ClinicalTrials.gov