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THe Comparison of Target Controlled Infusion of Propofol or Etomidate at General Anesthesia in Geriatric Patients

NCT02111265 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2014-04-14

No results posted yet for this study

Summary

Compare the efficacy and safety of closed-loop target controlled infusion of propofol or etomidate at general anesthesia in geriatric patients

Conditions

  • Adrenal Suppression
  • Hemodynamic Instability

Interventions

DRUG

Remifentanil

1. Remifentanil 0.1-0.2μg/ ( kg•min) is continuously pumped at steady speed for analgesia for induction and maintenance of anesthesia. 2. Remifentanil is stopped before skin closure

DRUG

Cisatracurium

1. Cisatracurium 0.15 mg/kg for induction and 0.12 mg/kg/h continuous infusion for maintenance of anesthesia. 2. Cisatracurium is stopped before skin closure.

DRUG

Sufentanil

Before skin closure, remifentanil is stopped and sufentanyl 0.1μg/kg is given by intravenous injection.

DEVICE

Bispectral index(BIS) monitor

BiS is maintained at 40-60 during anesthesia.

Sponsors & Collaborators

  • Chinese Medical Association

    collaborator NETWORK

  • Second Affiliated Hospital of Xi'an Jiaotong University

    lead OTHER

Principal Investigators

  • He Jiaxuan · Department of Anesthesia, Second Affiliated Hospital of Xi'an Jiaotong University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-04-30
Primary Completion
2014-07-31
Completion
2014-07-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02111265 on ClinicalTrials.gov