The Cognitive Ageing Nutrition and Neurogenesis (CANN) Trial
NCT02525198 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 259
Last updated 2024-05-14
Summary
There is a dearth of research which takes a multi-compound approach to dietary interventions, in humans, aimed at improving outcome measures of cognition. Animal research in particular points towards fatty acids and flavonoids having a potentiating effect on each other, and possibly even being synergistic. Thus, study products will be administered in the present trial comprising both of these compounds, with a view to investigating their potential effects on cognition in older adults with mild cognitive impairment (MCI) or subjective memory impairment (SMI).
Conditions
- Mild Cognitive Impairment
- Subjective Memory Impairment
Interventions
- DIETARY_SUPPLEMENT
-
fatty acid/flavonoid blend
see arm description
- DIETARY_SUPPLEMENT
-
Placebo
see arm description
Sponsors & Collaborators
-
Swinburne University of Technology
collaborator OTHER -
University of Illinois at Chicago
collaborator OTHER -
University of East Anglia
lead OTHER
Principal Investigators
-
Anne Marie Minihane, PhD · Department of Nutrition, University of East Anglia, Norwich, U.K.
-
Andrew Scholey, PhD · Centre for Human Psychopharmacology, Swinburne University of Technology
-
Neal J Cohen, PhD · Beckman Institute, University of Illinois
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-08-01
- Primary Completion
- 2018-03-31
- Completion
- 2018-03-31
Countries
- United States
- Australia
- United Kingdom
Study Locations
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