Canola-Mediterranean Diet Study in T2DM

Summary

The purpose of the study is to assess whether a Mediterranean-type weight-loss diet, enriched with canola oil, high in plant protein, and low in carbohydrates will produce blood sugar control, reduce coronary heart disease (CHD) risk factors and maximize weight loss, better than conventional higher carbohydrate diets in overweight diabetic patients.

Conditions

• Type 2 Diabetes
• Obesity
• Overweight
• Cardiovascular Diseases

Interventions

BEHAVIORAL

A canola oil enriched mediterranean diet

The diet will be provided at 60% of calories estimated for stable body weight to encourage weight loss. A high protein canola oil-enriched test bread will be provided as a supplement.

BEHAVIORAL

A high wheat fiber diet

The diet will be provided at 60% of calories estimated for stable body weight to encourage weight loss. A whole wheat control bread will be provided as a supplement to participants

Sponsors & Collaborators

• University of Toronto

  collaborator OTHER

• Laval University

  collaborator OTHER

• University of Manitoba

  collaborator OTHER

• Canola Council of Canada

  collaborator OTHER

• Unity Health Toronto

  lead OTHER

Principal Investigators

• David J Jenkins, MD · St. Michael's Hospital / University of Toronto

• Cyril Kendall, PhD · University of Toronto

• Vladimir Vuksan, PhD · Unity Health Toronto

• Peter Jones, PhD · University of Manitoba

• Benoit Lamarche, PhD · Laval University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

21 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-10-31

Primary Completion

2016-12-14

Completion

2017-03-13

Countries

• Canada

Study Locations