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Study of Variation Over Time in the Oral Microbiome

NCT02049398 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 41

Last updated 2020-11-27

No results posted yet for this study

Summary

Background:

\- Normal bacteria and other tiny organisms are found in healthy human mouths. These are called oral microbiota. It is unclear exactly how the oral microbiota may affect health. For example, if the microbial composition is abnormal, it may lead to mouth conditions like periodontitis. Researchers want to study how the microbiota changes over time. This can help them plan future disease studies.

Objectives:

\- To see if and how oral microbiota change over time.

Eligibility:

\- Forty adult employees of the National Cancer Institute Shady Grove.

Design:

* For 12 hours before the first visit, participants will not eat or drink (except water). They will not brush, floss, use mouthwash, chew gum, eat lozenges or candies, smoke cigarettes, or chew tobacco.
* At the first visit, participants will:
* Be given a saliva collector. They will spit 2 mL of saliva into it.
* Fill out an online questionnaire.
* Every 2 months, participants will visit the clinic and repeat visit 1.
* The study ends after 1 year.

Sponsoring Institute: National Cancer Institute

Conditions

  • Microbiota
  • Oral Health
  • Body Mass Index

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    lead NIH

Principal Investigators

  • Christian Abnet, Ph.D. · National Cancer Institute (NCI)

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-01-28
Primary Completion
2015-09-16
Completion
2015-12-23

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02049398 on ClinicalTrials.gov