Estimate the Relationship Between Oral Microbiota and Stroke
NCT06479915 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 170
Last updated 2025-08-07
Summary
Oral bacteria constitute the second largest population of the human microbiome. Recent studies have identified their role in the development of systemic diseases, such as cardiovascular and cerebrovascular diseases. Streptococcus Mutans (SM) is considered the primary pathogen responsible for dental caries. Furthermore, in cases of oral inflammatory diseases, SM has been found to invade the bloodstream and disseminate, leading to systemic diseases. Against this backdrop, this study aims to investigate disparities in oral flora between stroke patients and healthy individuals by collecting saliva samples from both groups.
Conditions
- Stroke
- Microbial Disease
Sponsors & Collaborators
-
First Affiliated Hospital of Fujian Medical University
collaborator OTHER -
Fujian Medical University
lead OTHER
Principal Investigators
-
XiaoJing Huang · School and Hospital of Stomatology,Fujian Medical University,fuzhou,Fujian Province,350002,China
Eligibility
- Min Age
- 18 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-04-01
- Primary Completion
- 2025-02-28
- Completion
- 2025-06-30
Countries
- China
Study Locations
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