MedTrace Logo

Oral Alkali Production and Caries Prevention in Children (Longitudinal)

NCT02398695 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 232

Last updated 2018-11-13

No results posted yet for this study

Summary

The fact that dental caries remains a major public health problem mandates that oral-health researchers explore new strategies for assessment of caries risk, as well as for caries prevention and management. Dental caries occurs when acids produced by bacterial glycolysis of dietary carbohydrates causes demineralization of the tooth enamel. A major focus of caries research has been on identifying and characterizing acid-generating bacteria and the mechanisms of acid resistance. The purpose of this study is to investigate over time the relationship between alkali production and caries.

Conditions

  • Dental Caries

Interventions

OTHER

Oral Samples

Oral samples of saliva, dental plaque and DNA will be collected between the two groups.

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • National Institute of Dental and Craniofacial Research (NIDCR)

    collaborator NIH

  • University of Florida

    lead OTHER

Principal Investigators

  • Marcelle Nascimento, DDS, MS, PhD · University of Florida

Eligibility

Min Age
2 Years
Max Age
7 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-10-31
Primary Completion
2015-08-27
Completion
2015-08-27

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02398695 on ClinicalTrials.gov