the Prevalence of Oral Manifestation in Patients With SARS-CoV2 Infection
NCT04893694 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 385
Last updated 2021-08-24
Summary
The SARS-Cov2 virus was identified in china at the end of 2019 and spread worldwide causing a global pandemic. Current research showed that SARS-Cov2 virus invades human cells via the receptor angiotensin-converting enzyme 2 (ACE2) through scRNA-seq data analyses. The study identified the organs that are at risk and are vulnerable to SARS-CoV-2 infection. Therefore, cells with ACE2 receptor distribution may become host cells for the virus and cause inflammatory response in related organs and tissues, such as the tongue mucosa and salivary glands. These results suggest that oral mucosa could be a target of SARS-CoV-2 infection
Conditions
- SARS-CoV2 Infection
Sponsors & Collaborators
-
Ministry of Health and Population, Egypt
collaborator OTHER_GOV -
Fayoum University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-05-20
- Primary Completion
- 2021-06-20
- Completion
- 2021-07-15
Countries
- Egypt
Study Locations
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