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The Salivary Microbiome in Children With Type 1 Diabetes Mellitus

NCT03908021 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 66

Last updated 2022-03-29

No results posted yet for this study

Summary

Aims: To profile the oral microbiome of children with type 1 diabetes mellitus, and to compare it to healthy children while taking into account other aspects of the oral environment.

Research: exploring the differences between oral microflora of children with type 1 diabetes mellitus and control healthy children using salivary microbiome. The investigators will furthermore intend to analyze the differences of salivary flow rate, pH, glucose, calcium, inorganic phosphate and urea between the two groups.

Conditions

  • Type1 Diabetes Mellitus

Interventions

DIAGNOSTIC_TEST

Microbiome analysis and 16S rRNA gene-based analysis

microbial DNA is extracted from the saliva and 16s library is prepared for sequencing.

Sponsors & Collaborators

  • Hadassah Medical Organization

    lead OTHER

Eligibility

Min Age
5 Years
Max Age
15 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-08-01
Primary Completion
2021-08-30
Completion
2021-12-30

Countries

  • Israel

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03908021 on ClinicalTrials.gov