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Effect of Two Different Isoflavone Supplement Preparations on Gene-expression in Postmenopausal Women

NCT01556737 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 72

Last updated 2012-10-31

No results posted yet for this study

Summary

Alleged benefits experienced after the consumption of soy in Asian countries have been attributed to the isoflavone content of soy products. Amongst other benefits, isoflavones are believed to relieve menopausal symptoms and are therefore often consumed in supplement form in Western countries. These supplements contain relatively high amounts of isoflavones and are on the market in different compositions. The question is whether supplements with different compositions exert similar effects or whether the effects differ substantially.

Conditions

  • Postmenopause

Interventions

DIETARY_SUPPLEMENT

High daidzein supplement

8 weeks exposure to the supplement, daily 100 mg of isoflavones

DIETARY_SUPPLEMENT

High genistein supplement

8 weeks exposure to the supplement, daily 100 mg of isoflavones

Sponsors & Collaborators

  • Wageningen University

    lead OTHER

Principal Investigators

  • Pieter van 't Veer, Prof · Wageningen University

Study Design

Allocation
RANDOMIZED
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
50 Years
Max Age
70 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-11-30
Primary Completion
2012-09-30
Completion
2012-09-30

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01556737 on ClinicalTrials.gov