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Role of Indoor Pollutants on House Dust Mite Allergic Asthma

NCT01019291 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2015-03-27

No results posted yet for this study

Summary

It seems that the aldehydes and NO2, at the levels found indoor, could be the aggravating factors for an allergic response. However this effect has not been demonstrated. The investigators plan to study the effect of exposure to standard doses of these pollutants on the bronchial reactivity as measured by bronchial challenge tests with dust mite extract in volunteers asthmatic, allergic to house dust mite.

Conditions

  • Allergic Asthma
  • Allergy to House Dust Mite

Interventions

OTHER

Formaldehyde and NO2 (Exposure to indoor pollutants)

Exposure to indoor pollutants (Formaldehyde and NO2) in a randomized way, followed by bronchial challenge test with house dust mite extract.

OTHER

Placebo (Exposure to indoor pollutants)

Exposure to indoor pollutants (placebo) in a randomized way, followed by bronchial challenge test with house dust mite extract.

Sponsors & Collaborators

  • University Hospital, Strasbourg, France

    lead OTHER

Principal Investigators

  • Frederic DE BLAY, MD · Service de Pneumologie, Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg

Study Design

Allocation
RANDOMIZED
Masking
DOUBLE

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01019291 on ClinicalTrials.gov