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Environmental Pollutants and Their Effects on Respiratory Allergy

NCT04902989 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 93

Last updated 2021-05-26

No results posted yet for this study

Summary

In Latin America and the Caribbean, more than 100 million people are exposed to higher levels of pollution than those recommended by WHO. The objective of the study is to determine the relationship between exposure to environmental pollutants and the prevalence and exacerbation of respiratory allergy. It is an observational, prospective, longitudinal and descriptive study that will include subjects older than 6 years who come to the consultation of the Regional Center for Allergy and Clinical Immunology with a diagnosis of respiratory allergy, positive skin tests and who live in Monterrey and its metropolitan area. After verbal assent, the subject's address and work area will be registered, the Rhinitis Control Assessment Test and the Asthma Control Test as well as spirometry will be made. The geolocation of industries and avenues near the address and work area of subjects will be carried out, as well as the determination of pollutants and pollens by the Integral Monitoring System (SIMA) and the Pollen Sense device. Subsequently, the correlation between exposure to pollutants and respiratory allergy will be analyzed. Dispersion models will be built considering pollutants and climatic factors (precipitation, wind speed, humidity and temperature). By carrying out this project, it will be possible to contribute to the identification of the factors that lead to the development and exacerbation of allergic respiratory diseases and subsequently propose the implementation of measures for their control and recommendations for prevention to the population.

Conditions

  • Allergic Rhinitis
  • Allergic Asthma
  • Pollution; Exposure

Interventions

OTHER

pollutants and pollen

Pollutants (ozone, SO3, NO3, PM2.5, diesel exhaust particles)

Sponsors & Collaborators

  • Medicina

    collaborator OTHER

  • Cindy Elizabeth de Lira-Quezada

    lead OTHER

Principal Investigators

  • Sandra N Gonzalez Diaz, MD,PhD · Head of the Allergy and Clinical Immunology Service

Eligibility

Min Age
6 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-03-10
Primary Completion
2021-08-10
Completion
2022-08-10

Countries

  • Mexico

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04902989 on ClinicalTrials.gov